StressMarq/BIX-01294/SIH-347-5MG/5-mg
商品编号：
SIH-347-5MG
市场价：
¥1760.00
美元价：
1056.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | BIX-01294 |
| Description | HMTinhibitor |
| Purity | >98% |
| CASNo. | 935693-62-2 |
| MolecularFormula | C28H38N6O2*3HCl |
| MolecularWeight | 600.02 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | MaybedissolvedinDMSO(100mM)orWater(100mM) |
| Source | Synthetic |
| Appearance | Creamsolid |
| SMILES | CN1CCCN(CC1)C2=NC3=CC(=C(C=C3C(=N2)NC4CCN(CC4)CC5=CC=CC=C5)OC)OC.Cl.Cl.Cl |
| InChI | InChI=1S/C28H38N6O2/c1-32-12-7-13-34(17-16-32)28-30-24-19-26(36-3)25(35-2)18-23(24)27(31-28)29-22-10-14-33(15-11-22)20-21-8-5-4-6-9-21/h4-6,8-9,18-19,22H,7,10-17,20H2,1-3H3,(H,29,30,31) |
| InChIKey | OSXFATOLZGZLSK-UHFFFAOYSA-N |
| SafetyPhrases | Classification:Caution–Substancenotyetfullytested.SafetyPhrases:S22-DonotbreathedustS36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotectionS24/25-Avoidcontactwithskinandeyes |
| CiteThisProduct | BIX-01294(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-347) |
BIOLOGicalDescription
| AlternativeNames | 2-(Hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6,7-dimethoxy-N-[1-(phenylmethyl)-4-piperidinyl]-4-quinazolinaminetrihydrochloride;N-(1-Benzyl-4-piperidinyl)-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)-4-quinazolinaminetrihydrochloride |
| ResearchAreas | Cancer,CellSignaling,Epigenetics |
| PubChemID | 25150857 |
| ScientificBackground | G9a-likeproteinandG9ahistonelysinemethyltransferaseinhibitor(ICvaluesare0.7and1.7µMrespectively)thatdisplaysnoactivityatotherhistonemethyltransferasesupto37µM.ModulatesH3K9me2levelsinmammaliancellsandpotentiatesinductionofpluripotentstemcellsfromsomaticcellsinvitro. |
| References | 1.KubicekS.,etal.(2007)MolCell.25(3):473-481. 2.ShiY.,etal.(2008)CellStemCell.3(5):568-574. 3.ChangY.,etal.(2009)NatStructMolBiol.16(3):312-317. |
ProductImages
ChemicalstructureofBIX-01294(SIH-347),aHistonemethyltransferaseinhibitor.CAS#:935693-62-2.MolecularFormula:C28H38N6O2*3HCl.MolecularWeight:600.02g/mol.
ProductCitations(0)
Currentlytherearenocitationsforthisproduct.
品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
