StressMarq/Bafilomycin A1/SIH-391-100UG/100-µg
商品编号：
SIH-391-100UG
市场价：
¥1000.00
美元价：
600.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | BafilomycinA1 |
| Description | Autophagyinhibitor |
| Purity | >95% |
| CASNo. | 88899-55-2 |
| MolecularFormula | C35H58O9 |
| MolecularWeight | 622.84 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | Solublein100%ethanol,methanolorDMSO. |
| Source | Synthetic |
| Appearance | Whitepowdertocolorlessfilm. |
| SMILES | [[email protected]]1(O[[email protected]@H]([[email protected]]([[email protected]](O)C1)C)C(C)C)(O)[[email protected]]([[email protected]](O)[[email protected]@H]([[email protected]]2OC(=O)C(=C/C(=C/[[email protected]]([[email protected]@H](O)[[email protected]](CC(=C/C=C/[[email protected]@H]2OC) |
| InChI | InChI=1S/C35H58O9/c1-19(2)32-24(7)27(36)18-35(40,44-32)26(9)31(38)25(8)33-28(41-10)14-12-13-20(3)15-22(5)30(37)23(6)16-21(4)17-29(42-11)34(39)43-33/h12-14,16-17,19,22-28,30-33,36-38,40H,15,18H2,1-11H |
| InChIKey | XDHNQDDQEHDUTM-JQWOJBOSSA-N |
| SafetyPhrases | Classification:D2B-ToxicMaterialCausingOtherToxicEffectsIrritantSafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection.Hazardstatements:H315-Causesskinirritation.H319-Causesseriouseyeirritation.H335-Maycauserespiratoryirritation.Precautionarystatements:P261-Avoidbreathingdust/fume/gas/mist/vapours/spray.P264-Washskinthoroughlyafterhandling.P271-Useonlyoutdoorsorinawell-ventilatedarea.P280-Wearprotectivegloves/eyeprotection/faceprotection.P302+P352-IFONSKIN:Washwithplentyofsoapandwater.P304+P340-IFINHALED:Removevictimtofreshairandkeepatrestinapositioncomfortableforbreathing.P305+P351+P338-IFINEYES:Rinsecautiouslywithwaterforseveralminutes.Removecontactlenses,ifpresentandeasytodo.Continuerinsing.P312-CallaPOISONCENTERordoctor/physicianifyoufeelunwell.P321-Specifictreatment(seesupplementalfirstaidinstructionsonthislabel).P332+P313-Ifskinirritationoccurs:Getmedicaladvice/attention.P337+P313-Ifeyeirritationpersists:Getmedicaladvice/attention.P362-Takeoffcontaminatedclothingandwashbeforereuse.P403+P233-Storeinawell-ventilatedplace.Keepcontainertightlyclosed.P405-Storelockedup.P501-Disposeofcontents/containertoanapprovedwastedisposalplant. |
| CiteThisProduct | BafilomycinA1(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-391) |
BIOLOGicalDescription
| AlternativeNames | (3Z,5E,7R,8S,9S,11E,13E,15S,16R)-8-Hydroxy-16-[(1S,2R,3S)-2-hydroxy-1-methyl-3-[(2R,4R,5S,6R)-tetrahydro-2,4-dihydroxy-5-methyl-6-(1-methylethyl)-2H-pyran-2-yl]butyl]-3,15-dimethoxy-5,7,9,11-tetramethyloxacyclohexadeca-3,5,11,13-tetraen-2-one |
| ResearchAreas | Cancer,Autophagy |
| PubChemID | 6436223 |
| ScientificBackground | BafilomycinA1isamacrolideantibioticderivedfromStreptomycesgriseus.Itselectivelyinhibitsvacuolar-typeH+-ATPases,allowingittobeusedtodifferentiatebetweendifferenttypesofATPases.Bafilomycinalsoactstoinhibitautophagybyeitherblockingautophagosome-lysosomefusion,orbyblockinglysosomaldegradation. |
| References | 1.GagliardiS.,etal.(1999).CurrMedChem.6(12):1197-212. 2.FassE.,etal.(2006).JBiolChem.281(47):36303-16. 3.YamamotoA.,etal.(1998).CellStructFunct.23(1):33-42. |
ProductImages
ChemicalstructureofBafilomycinA1(SIH-391),aAutophagyinhibitor.CAS#:88899-55-2.MolecularFormula:C35H58O9.MolecularWeight:622.84g/mol.
ProductCitations(0)
Currentlytherearenocitationsforthisproduct.
品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
