STRESS MARQ/b-AP15（NSC-687852）/SIH-339-25MG/25MG
商品编号：
SIH-339-25MG
市场价：
¥6080.00
美元价：
3648.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | b-AP15(NSC-687852) |
| Description | DUBinhibitor |
| Purity | >98% |
| CASNo. | 1009817-63-3 |
| MolecularFormula | C22H17N3O6 |
| MolecularWeight | 419.4 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | Solublein35mg/mlDMSO |
| Source | Synthetic |
| Appearance | PaleYellowSolid |
| SMILES | C=CC(=O)N1C/C(=CC2=CC=C(C=C2)[N+](=O)[O-])/C(=O)/C(=C/C3=CC=C(C=C3)[N+](=O)[O-])/C1 |
| InChI | InChI=1S/C22H17N3O6/c1-2-21(26)23-13-17(11-15-3-7-19(8-4-15)24(28)29)22(27)18(14-23)12-16-5-9-20(10-6-16)25(30)31/h2-12H,1,13-14H2/b17-11+,18-12+ |
| InChIKey | GFARQYQBWJLZMW-JYFOCSDGSA-N |
| SafetyPhrases | Classification:Caution–Substancenotyetfullytested.SafetyPhrases:S22-DonotbreathedustS36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotectionS24/25-Avoidcontactwithskinandeyes |
| CiteThisProduct | b-AP15(NSC-687852)(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-339) |
BIOLOGicalDescription
| AlternativeNames | (3E,5E)-1-Acryloyl-3,5-bis(4-nitrobenzylidene)-4-piperidinone |
| ResearchAreas | Cancer,Apoptosis |
| PubChemID | 5351435 |
| ScientificBackground | Abrogatesthedeubiquitinatingactivityofthe19SregulatoryparticlebyinhibitingubiquitinC-terminalhydrolase5(UCHL5)andubiquitin-specificpeptidase14(USP14)resultinginaccumulationofpolyubiquitinincells.b-AP15inducestumorcellapoptosisandtumorprogressioninfourdifferentsolidtumormodelsinvivo. |
| References | 1.D’ArcyP.,etal.(2011)NatureMedicine17:1636. |
ProductImages
Chemicalstructureofb-AP15(NSC-687852)(SIH-339),aDUBinhibitor.CAS#:1009817-63-3.MolecularFormula:C22H17N3O6.MolecularWeight:419.4g/mol.
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
