StressMarq/Axitinib/SIH-494-10MG/10-mg
商品编号：
SIH-494-10MG
市场价：
¥4000.00
美元价：
2400.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | Axitinib |
| Description | VEGFRkinaseinhibitor |
| Purity | >98%(HPLC) |
| CASNo. | 319460-85-0 |
| MolecularFormula | C22H18N4OS |
| MolecularWeight | 386.5 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | Solubleto25mMinDMSO |
| Source | Synthetic |
| Appearance | Whitetotanpowder |
| SMILES | CNC(=O)C1=CC=CC=C1SC2=CC3=C(C=C2)C(=NN3)/C=C/C4=CC=CC=N4 |
| InChI | InChI=1S/C22H18N4OS/c1-23-22(27)18-7-2-3-8-21(18)28-16-10-11-17-19(25-26-20(17)14-16)12-9-15-6-4-5-13-24-15/h2-14H,1H3,(H,23,27)(H,25,26)/b12-9+ |
| InChIKey | RITAVMQDGBJQJZ-FMIVXFBMSA-N |
| SafetyPhrases | Classification:Acutetoxicity,Oral(Category4),H302Acuteaquatictoxicity(Category1),H400Chronicaquatictoxicity(Category1),H410SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection.Hazardstatements:H302Harmfulifswallowed.H410VerytoxictoaquaticlifewithlonglastingeffectsPrecautionarystatements:P264Washskinthoroughlyafterhandling.P270Donoteat,drinkorsmokewhenusingthisproduct.P273Avoidreleasetotheenvironment.P301+P312IFSWALLOWED:CallaPOISONCENTERordoctor/physicianifyoufeelunwell.P330Rinsemouth.P391Collectspillage.P501Disposeofcontents/containertoanapprovedwastedisposalplant. |
| CiteThisProduct | Axitinib(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-494) |
BIOLOGicalDescription
| AlternativeNames | AG-013736,N-Methyl-2-((3-((1E)-2-(pyridin-2-yl)ethenyl)-1H-indazol-6-yl)sulfanyl)benzamide,N-Methyl-[[3[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]-benzamide |
| ResearchAreas | Cancer,Apoptosis,CancerGrowthInhibitors,CardiovascularSystem,CellSignaling,TyrosineKinaseInhibitors |
| PubChemID | 6450551 |
| ScientificBackground | AxitinibisapotentandselectivetyrosinekinaseinhibitorthatblocksVEGFreceptors1,2and3.IthasalsobeenshowntoinhibitPDGFR-βandc-Kit. |
| References | 1.Hu-LoweD.D.,etal.(2008)Clin.CancerRes:J.Am.Ass.CancerRes.14(22):7272–7283. |
ProductImages
ChemicalstructureofAxitinib(SIH-494),aVEGFRkinaseinhibitor.CAS#:319460-85-0.MolecularFormula:C22H18N4OS.MolecularWeight:386.5g/mol.
ProductCitations(0)
Currentlytherearenocitationsforthisproduct.
品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
