StressMarq/Auranofin/SIH-493-50MG/50-mg
商品编号：
SIH-493-50MG
市场价：
¥1500.00
美元价：
900.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | Auranofin |
| Description | IKKkinaseinhibitor |
| Purity | >98%(HPLC) |
| CASNo. | 34031-32-8 |
| MolecularFormula | C20H34AuO9PS |
| MolecularWeight | 678.5 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | SolubleinDMSO(5mg/ml)or100%ethanol(4mg/ml) |
| Source | Synthetic |
| Appearance | Whitesolid |
| SMILES | CCP(=[Au]S[[email protected]]1[[email protected]@H]([[email protected]]([[email protected]@H]([[email protected]](O1)COC(=O)C)OC(=O)C)OC(=O)C)OC(=O)C)(CC)CC |
| InChI | InChI=1S/C14H20O9S.C6H15P.Au/c1-6(15)19-5-10-11(20-7(2)16)12(21-8(3)17)13(14(24)23-10)22-9(4)18;1-4-7(5-2)6-3;/h10-14,24H,5H2,1-4H3;4-6H2,1-3H3;/q;;+1/p-1 |
| InChIKey | AUJRCFUBUPVWSZ-UHFFFAOYSA-M |
| SafetyPhrases | Classification:Acutetoxicity,Oral(Category3),H301Reproductivetoxicity(Category2),H361SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection.Hazardstatements:H301Toxicifswallowed.H361SUSPectedofdamagingfertilityortheunbornchild.Precautionarystatements:P201Obtainspecialinstructionsbeforeuse.P202Donothandleuntilallsafetyprecautionshavebeenreadandunderstood.P264Washskinthoroughlyafterhandling.P270Donoteat,drinkorsmokewhenusingthisproduct.P281Usepersonalprotectiveequipmentasrequired.P301+P310IFSWALLOWED:ImmediatelycallaPOISONCENTERordoctor/physician.P308+P313IFexposedorconcerned:Getmedicaladvice/attention.P321Specifictreatment(seesupplementalfirstaidinstructionsonthislabel).P330Rinsemouth.P405Storelockedup.P501Disposeofcontents/containertoanapprovedwastedisposalplant. |
| CiteThisProduct | Auranofin(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-493) |
BIOLOGicalDescription
| AlternativeNames | 1-Thio-β-D-glucopyranosatotriethylphosphinegold-2,3,4,6-tetraacetate,3,4,5-Triacetyloxy-6-(acetyloxymethyl)oxane-2-thiolatetriethylphosphanium,SKF39162 |
| ResearchAreas | Cancer,Apoptosis,CancerGrowthInhibitors,CellSignaling,TyrosineKinaseInhibitors |
| PubChemID | 24199313 |
| ScientificBackground | Auranofinisderivativeofgoldandhasbeenwidelyusedasananti-arthriticdrug.Itinhibitsbothleukocyteactivationpathwaysatmultiplesitesandthereleaseofinflammatorymediatorsfromhumanmacrophages,basophils,andpulmonarymastcells.Auranofinhasbeenshowntoinhibithumanneutrophil5-lipoxygenase,thioredoxinreductase(TrxR),IκBkinase(IKK). |
| References | 1.BettsW.H.,HurstN.P.,MurphyG.A.,&ClelandL.G.(1990)Biochem.Pharm.39(7).1233–1237. 2.RudkowskiR.,ZieglerJ.B.,GrahamG.G.,&ChampionG.D.(1991)Biochem.Pharm.41(12):1921–1929. |
ProductImages
ChemicalstructureofAuranofin(SIH-493),aIKKkinaseinhibitor.CAS#:34031-32-8.MolecularFormula:C20H34AuO9PS.MolecularWeight:678.5g/mol.
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
