StressMarq/Astemizole/SIH-302-10MG/10-mg
商品编号：
SIH-302-10MG
市场价：
¥1220.00
美元价：
732.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | Astemizole |
| Description | Hergchannelblocker |
| Purity | >98% |
| CASNo. | 68844-77-9 |
| MolecularFormula | C28H31FN4O |
| MolecularWeight | 458.57 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | Solubleto100mMinDMSOandto25mMinethanol |
| Source | Synthetic |
| Appearance | Whitesolid |
| SMILES | COC1=CC=C(C=C1)CCN2CCC(CC2)NC3=NC4=CC=CC=C4N3CC5=CC=C(C=C5)F |
| InChI | InChI=1S/C28H31FN4O/c1-34-25-12-8-21(9-13-25)14-17-32-18-15-24(16-19-32)30-28-31-26-4-2-3-5-27(26)33(28)20-22-6-10-23(29)11-7-22/h2-13,24H,14-2 |
| InChIKey | GXDALQBWZGODGZ-UHFFFAOYSA-N |
| SafetyPhrases | Classification:Caution:Substancenotyetfullytested.SafetyPhrases:S22-DonotbreathedustS24/25-AvoidcontactwithskinandeyesS36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotectionRiskPhrases:R62-PossIBLeriskofimpairedfertilityHazardPhrases:H315-H319-H335PrecautionaryPhrases:P261-P305+P351+P338 |
| CiteThisProduct | Astemizole(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-302) |
BIOLOGicalDescription
| AlternativeNames | 1-(4-Fluorobenzyl)-N-{1-[2-(4-methoxyphenyl)ethyl]-4-piperidinyl}-1H-benzimidazol-2-amine,Hismanal |
| ResearchAreas | IonChannels,Neuroscience |
| PubChemID | 2247 |
| ScientificBackground | Astemizoleisasecondgenerationantihistaminedrugwhichhasalongdurationofaction.ItbindstohistamineH1-receptorsitesinthegastrointestinaltract,uterus,bloodvesselsandbronchialmuscle.Itdoesnotcrosstheblood-brainbarrier,andthebindingisprimarilyintheperipheralnervoussystem(1).ItismetabolizedbyCYP3A4(2). |
| References | 1.LaduronP.M.,JanssenP.F.,CommerenW.andLeysenJ.E.(1982)MolPharmacol.21(2):294-300. 2.MaysumotoS.,YamazoeY.(2001)Br.JClinPharamcol.51(2):133-142. |
ProductImages
ChemicalstructureofAstemizole(SIH-302),aHergchannelblocker.CAS#:68844-77-9.MolecularFormula:C28H31FN4O.MolecularWeight:458.57g/mol.
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
