StressMarq/AR A014418/SIH-492-25MG/25-mg
商品编号：
SIH-492-25MG
市场价：
¥7500.00
美元价：
4500.00
产品分类：
酚
公司分类：
hydroxybenzene
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | ARA014418 |
| Description | GSK-3kinaseinhibitor |
| Purity | >95%(HPLC) |
| CASNo. | 487021-52-3 |
| MolecularFormula | C12H12N4O4S |
| MolecularWeight | 308.3 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | SolubleinDMSO,methanol,100%ethanolorethylacetate |
| Source | Synthetic |
| Appearance | Whitetooff-whitesolid |
| SMILES | COC1=CC=C(C=C1)CNC(=O)NC2=NC=C(S2)[N+](=O)[O-] |
| InChI | InChI=1S/C12H12N4O4S/c1-20-9-4-2-8(3-5-9)6-13-11(17)15-12-14-7-10(21-12)16(18)19/h2-5,7H,6H2,1H3,(H2,13,14,15,17) |
| InChIKey | YAEMHJKFIIIULI-UHFFFAOYSA-N |
| SafetyPhrases | Classification:Acutetoxicity,Oral(Category4),H302Skinirritation(Category2),H315Seriouseyedamage(Category1),H318Specifictargetorgantoxicity-singleexposure(Category3),Respiratorysystem,H335SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection.Hazardstatements:H302Harmfulifswallowed.H315Causesskinirritation.H318Causesseriouseyedamage.H335Maycauserespiratoryirritation.Precautionarystatements:P261Avoidbreathingdust/fume/gas/mist/vapours/spray.P264Washskinthoroughlyafterhandling.P270Donoteat,drinkorsmokewhenusingthisproduct.P271Useonlyoutdoorsorinawell-ventilatedarea.P280Wearprotectivegloves/eyeprotection/faceprotection.P301+P312IFSWALLOWED:CallaPOISONCENTERordoctor/physicianifyoufeelunwell.P302+P352IFONSKIN:Washwithplentyofsoapandwater.P304+P340IFINHALED:Removevictimtofreshairandkeepatrestinapositioncomfortableforbreathing.P305+P351+P338IFINEYES:Rinsecautiouslywithwaterforseveralminutes.Removecontactlenses,ifpresentandeasytodo.Continuerinsing.P310ImmediatelycallaPOISONCENTERordoctor/physician.P321Specifictreatment(seesupplementalfirstaidinstructionsonthislabel).P330Rinsemouth.P332+P313Ifskinirritationoccurs:Getmedicaladvice/attention.P362Takeoffcontaminatedclothingandwashbeforereuse.P403+P233Storeinawell-ventilatedplace.Keepcontainertightlyclosed.P405Storelockedup.P501Disposeofcontents/containertoanapprovedwastedisposalplant. |
| CiteThisProduct | ARA014418(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-492) |
BIOLOGicalDescription
| AlternativeNames | N-(4-Methoxybenzyl)-N′-(5-nitro-1,3-thiazol-2-yl)urea |
| ResearchAreas | Cancer,Apoptosis,CancerGrowthInhibitors,CellSignaling,TyrosineKinaseInhibitors |
| PubChemID | 448014 |
| ScientificBackground | ARA014418isahighlyselectiveglycogensynthasekinase3(GSK-3)inhibitor.GSK-3isaserine/threoninekinasethathasbeenimplicatedinpathologicalconditionssuchasdiabetesandAlzheimer′sdisease.ARA014418iscellpermeable. |
| References | 1.BhatR.V.,&BuddS.L.(2002)Neuro-Signals.11(5):251–261. 2.GouldT.D.,EinatH.,BhatR.,&ManjiH.K.(2004)Int.J.Neuropsychopharmacology(CINP).7(4):387–390. |
ProductImages
ChemicalstructureofARA014418(SIH-492),aGSK-3kinaseinhibitor.CAS#:487021-52-3.MolecularFormula:C12H12N4O4S.MolecularWeight:308.3g/mol.
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
