StressMarq/Anti-AKT3 Antibody/SPC-1102D-ALP/100-µl-免疫在线蚂蚁淘旗下平台

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StressMarq/Anti-AKT3 Antibody/SPC-1102D-ALP/100-µl

商品编号： SPC-1102D-ALP

品牌： StressMarq Biosciences

市场价： ¥6720.00

美元价： 4032.00

产地：美国(厂家直采)

公司：

产品分类：酚

公司分类： hydroxybenzene

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Overview:

Product Name AKT3 Antibody

Description

Rabbit Anti-Human AKT3 Polyclonal

Species Reactivity Human, Mouse

Applications WB, AM

Antibody Dilution WB (1:250); optimal dilutions for assays should be determined by the user.

Host Species Rabbit

Immunogen Species Human

Immunogen Synthetic peptide of human Akt3 (AA402-416)

Conjugates

Alkaline Phosphatase, APC, ATTO 390, ATTO 488, ATTO 565, ATTO 594, ATTO 633, ATTO 655, ATTO 680, ATTO 700, Biotin, FITC, HRP, PE/ATTO 594, PerCP, RPE, Streptavidin, Unconjugated

Properties

Storage Buffer	PBS pH7.4, 50% glycerol, 0.025% Thimerosal
Storage Temperature	-20ºC
Shipping Temperature	Blue Ice or 4ºC
Purification	Peptide Affinity Purified
Clonality	Polyclonal
Specificity	Detects 55.775 kDa.
Cite This Product	StressMarq Biosciences Cat# SPC-1102, RRID: AB_2710235
Certificate of Analysis	A 1:250 dilution of SPC-1102 was sufficient for detection of AKT3 in 10 µg of human A549 cell line lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.

Biological Description

Alternative Names	Akt3 antibody, AKT3 kinase antibody, AKT3_HUMAN antibody, PKB gamma antibody, PKBG antibody, PRKBG antibody, Protein kinase Akt-3 antibody, Protein kinase B gamma antibody, RAC gamma antibody, RAC gamma serine/threonine protein kinase antibody, RACPK Gamma antibody, Serine threonine protein kinase Akt 3 antibody, STK 2 antibody, STK-2 antibody, STK2 antibody, V akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma) antibody
Cellular Localization	Cytoplasm, Membrane
Accession Number	NP_005456
Gene ID	10000
Swiss Prot	Q9Y243
Scientific Background	AKT3 is Ser/Thr Kinase that is activated by PIP2 produced by PI3K, leading to translocation of AKT3 to the plasma membrane where it can be activated by S/T phosphorylation by PDK1/2. It is a regulator of cell signalling events such as proliferation, differentiation, apoptosis, tumourigenesis and also plays a role in brain development and in glucose metabolism, in response to insulin and a variety of growth factors such as PDGF and IGF-1. It is upregulated in a number of cancers.

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AP (Alkaline Phosphatase)

Properties:

Broad enzymatic activity for phosphate esters of alcohols, amines, pyrophosphate, and phenols
Commonly used to dephosphorylate the 5’-termini of DNA and RNA to prevent self-ligation
Catalyzes the conversion of:
- Chromogenic substrates (e.g. pNPP, naphthol AS-TR phosphate, BCIP) into coloured products
- Fluorogenic substrates (e.g. 4-methylumbelliferyl phosphate) into fluorescent products
Molecular weight: 140 kDa
Applications: Western blot, immunohistochemistry, and ELISA

AP Datasheet

品牌介绍

StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。

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