StressMarq/Anti-AKT1 Antibody (pTyr315)/SPC-911D-BI/100-µl-免疫在线蚂蚁淘旗下平台

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StressMarq/Anti-AKT1 Antibody (pTyr315)/SPC-911D-BI/100-µl

商品编号： SPC-911D-BI

品牌： StressMarq Biosciences

市场价： ¥6760.00

美元价： 4056.00

产地：美国(厂家直采)

公司：

产品分类：酚

公司分类： hydroxybenzene

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Overview:

ProductName AKT1Antibody(pTyr315)

Description

RabbitAnti-HumanAKT1(pTyr315)Polyclonal

SpeciesReactivity Human

Applications WB,AM

AntibodyDilution WB(1:250);optimaldilutionsforassaysshouldbedeterminedbytheuser.

HostSpecies Rabbit

ImmunogenSpecies Human

Immunogen Aphospho-specificpeptidecorrespondingtoresiduessurroundingTyr315ofhumanAkt1(AA312-318)

Conjugates

AlkalinePhosphatase,APC,ATTO390,ATTO488,ATTO565,ATTO594,ATTO633,ATTO655,ATTO680,ATTO700,Biotin,FITC,HRP,PE/ATTO594,PerCP,RPE,Streptavidin,Unconjugated

Properties

StorageBuffer	PBSpH7.4,50%glycerol,0.025%Thimerosal
StorageTemperature	-20ºC
ShippingTemperature	BlueIceor4ºC
Purification	PeptideAffinityPurified
Clonality	Polyclonal
Specificity	Detects55.686kDa.
CiteThisProduct	StressMarqBiosciencesCat#SPC-911,RRID:AB_2706797
CertificateofAnalysis	A1:250dilutionofSPC-911wassufficientfordetectionofAKT1(pTyr315)in10µgofHeLacelllysatebyECLimmunoblotanalysisusinggoatanti-rabbitIgG:HRPasthesecondaryantibody.

BIOLOGicalDescription

AlternativeNames	AKT1Antibody,AKT1_HumanAntibody,PKBAntibody,ProteinKinaseBAlphaAntibody,RACAntibody
ResearchAreas	Cancer,Apoptosis,CellSignaling,Metabolism,Metabolismprocesses,PKB/AKT,ProteinPhosphorylation,Serine/ThreonineKinases
CellularLocalization	Cytoplasm,Cellmembrane,Nucleus
AccessionNumber	NP_005154
GeneID	207
SwissProt	P31749
ScientificBackground	AKT1isaprotein-serine/threoninekinasewhichisinactiveinthecytoplasm.WhenPI3Kisactivatedbyextracellulargrowthfactors,AKT1isrecruitedtothecellmembraneandphosphorylatedtobecomeactive.Thisleadstotheinductionofsurvival,proliferation,angiogenesisandmetabolismpathways.AKT1isalsoinvolvedincell-cycleprogressionviaitsinhibitoryphosphorylationofcyclin-dependentkinasesandactivatoryphosphorylationofmTOR.UpregulationofthePI3K/AKTpathwayshasbeenimplicatedinavarietyofcancers.

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Biotin

Properties:

BindstetramericavidinproteinsincludingStreptavidinandneuravidinwithveryhighaffinity
Molarmass:244.31g/mol
Formula:C₁₀H₁₆N₂O₃S
Applications:Westernblot,immunohistochemistry,andELISA

BiotinDatasheet

品牌介绍

StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。

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