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当前位置: 首页 > 产品中心 > hydroxybenzene > STRESTMARQ/抗AKT1抗体(pTyr315)/SPC-911D-A390/100-µl
商品详细STRESTMARQ/抗AKT1抗体(pTyr315)/SPC-911D-A390/100-µl
STRESTMARQ/抗AKT1抗体(pTyr315)/SPC-911D-A390/100-µl
STRESTMARQ/抗AKT1抗体(pTyr315)/SPC-911D-A390/100-µl
商品编号: SPC-911D-A390
市场价: ¥6860.00
美元价: 4116.00
产地: 美国(厂家直采)
公司:
产品分类:
公司分类: hydroxybenzene
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

ProductNameAKT1Antibody(pTyr315)
Description

RabbitAnti-HumanAKT1(pTyr315)Polyclonal

SpeciesReactivityHuman
ApplicationsWB,AM
AntibodyDilutionWB(1:250);optimaldilutionsforassaysshouldbedeterminedbytheuser.
HostSpeciesRabbit
ImmunogenSpeciesHuman
ImmunogenAphospho-specificpeptidecorrespondingtoresiduessurroundingTyr315ofhumanAkt1(AA312-318)
ConjugatesAlkalinePhosphatase,APC,ATTO390,ATTO488,ATTO565,ATTO594,ATTO633,ATTO655,ATTO680,ATTO700,Biotin,FITC,HRP,PE/ATTO594,PerCP,RPE,Streptavidin,Unconjugated

Properties

StorageBufferPBSpH7.4,50%glycerol,0.025%Thimerosal
StorageTemperature-20ºC
ShippingTemperatureBlueIceor4ºC
PurificationPeptideAffinityPurified
ClonalityPolyclonal
SpecificityDetects55.686kDa.
CiteThisProductStressMarqBiosciencesCat#SPC-911,RRID:AB_2706797
CertificateofAnalysisA1:250dilutionofSPC-911wassufficientfordetectionofAKT1(pTyr315)in10µgofHeLacelllysatebyECLimmunoblotanalysisusinggoatanti-rabbitIgG:HRPasthesecondaryantibody.

BIOLOGicalDescription

AlternativeNamesAKT1Antibody,AKT1_HumanAntibody,PKBAntibody,ProteinKinaseBAlphaAntibody,RACAntibody
ResearchAreasCancer,Apoptosis,CellSignaling,Metabolism,Metabolismprocesses,PKB/AKT,ProteinPhosphorylation,Serine/ThreonineKinases
CellularLocalizationCytoplasm,Cellmembrane,Nucleus
AccessionNumberNP_005154
GeneID207
SwissProtP31749
ScientificBackgroundAKT1isaprotein-serine/threoninekinasewhichisinactiveinthecytoplasm.WhenPI3Kisactivatedbyextracellulargrowthfactors,AKT1isrecruitedtothecellmembraneandphosphorylatedtobecomeactive.Thisleadstotheinductionofsurvival,proliferation,angiogenesisandmetabolismpathways.AKT1isalsoinvolvedincell-cycleprogressionviaitsinhibitoryphosphorylationofcyclin-dependentkinasesandactivatoryphosphorylationofmTOR.UpregulationofthePI3K/AKTpathwayshasbeenimplicatedinavarietyofcancers.

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 ATTO390
Overview:
  • Highfluorescenceyield
  • LargeStokes-shift(89nm)
  • GoodphotostABIlity
  • Moderatelyhydrophilic
  • Goodsolubilityinpolarsolvents
  • Coumarinderivate,uncharged
  • Lowmolarmass:343.42g/mol 

ATTO390Datasheet

ATTO 390 Fluorescent Dye Excitation and Emission SpectraOpticalProperties:

λex =390nm

λem=479nm

εmax=2.4×104

Φf= 0.90

τfl =5.0ns

Brightness= 21.6

Laser =365or405nm

 

品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。