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当前位置: 首页 > 产品中心 > hydroxybenzene > StressMarq/Anti-AHA1p Antibody/SPC-204D/100-µl
商品详细StressMarq/Anti-AHA1p Antibody/SPC-204D/100-µl
StressMarq/Anti-AHA1p Antibody/SPC-204D/100-µl
StressMarq/Anti-AHA1p Antibody/SPC-204D/100-µl
商品编号: SPC-204D
市场价: ¥5460.00
美元价: 3276.00
产地: 美国(厂家直采)
公司:
产品分类:
公司分类: hydroxybenzene
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

ProductNameAHA1pAntibody
Description

RabbitAnti-YeastAHA1pPolyclonal

SpeciesReactivityYeast
ApplicationsWB
AntibodyDilutionWB(1:2500);optimaldilutionsforassaysshouldbedeterminedbytheuser.
HostSpeciesRabbit
ImmunogenSpeciesYeast
ImmunogenYeastAha1raisedagainstpeptide(CESQVKSNYTRGNQK)-KLHfusion
ConjugatesAlkalinePhosphatase,APC,ATTO390,ATTO488,ATTO565,ATTO594,ATTO633,ATTO655,ATTO680,ATTO700,Biotin,FITC,HRP,PE/ATTO594,PerCP,RPE,Streptavidin,Unconjugated

Properties

StorageBufferRabbitAntiserum,PBS,50%glycerol
StorageTemperature-20ºC
ShippingTemperatureBlueIceor4ºC
PurificationRabbitantiserum
ClonalityPolyclonal
SpecificityDetects~38kDa.Canrunupto45kDaonSDSPage.
CiteThisProductStressMarqBiosciencesCat#SPC-204,RRID:AB_2704181
CertificateofAnalysis0.5µg/mlofSPC-204wassufficientfordetectionofAha1pin20µgofW303yeastlysatebycolorimetricimmunoblotanalysisusingGoatanti-rabbitIgG:HRPasthesecondaryantibody.

BIOLOGicalDescription

AlternativeNamesActivatorof90kDaheatshockproteinATPasehomolog1Antibody,Aha1Antibody,SHSA1Antibody,HSPC322Antibody,p38Antibody
ResearchAreasCancer,HeatShock,CellSignaling,ChaperoneProteins,ProteinTrafficking
CellularLocalizationCytoplasm,EndoplasmicReticulum
AccessionNumberNP_010500.3
GeneID851800
SwissProtQ12449
ScientificBackgroundAha1isamemberoftheHSP90cochaperonefamily,andisthoughttostimulateHSP90ATPaseactivitybycompetingwithp23andotherco-chaperonesforHSP90binding(1,2).ItmayaffectastepintheendoplasmicreticulumtoGolgitrafficking.Aha1alsointeractswithHSPCA/HSP90andwiththecytoplasmictailofthevesicularstomatistisvirusglycoproteins(VSVG)(3).Aha1isexpressedinnumeroustissues,includingthebrain,heart,skeletalmuscle,andkidney,andatlowlevels,theliverandplacenta.Aha1mightbeapotentialtherapeuticstrategytoincreasesensitivitytoHSPinhibitors(4).
References1.HainzlO.,LapinaM.C.,BuchnerJ.,RichterK.(2009)JBiolChem.Epub.
2.HarstA.,LinH.,ObermannW.M.(2005)BiochemJ.387(pt.3):789-796.
3.LotzG.P.,BrychzyA.,HeinzS.,ObermannW.M.(2008)JCellSci.121(pt.5):717-723.
4.HolmesJ.L.,SharpS.Y.,HobbsS.,WorkmanP.(2008)CancerRes.68(4):1188-1197.

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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。