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当前位置: 首页 > 产品中心 > hydroxybenzene > StressMarq/AHA1 Protein/SPR-314C/2x100-µg
商品详细StressMarq/AHA1 Protein/SPR-314C/2x100-µg
StressMarq/AHA1 Protein/SPR-314C/2x100-µg
StressMarq/AHA1 Protein/SPR-314C/2x100-µg
商品编号: SPR-314C
市场价: ¥10200.00
美元价: 6120.00
产地: 美国(厂家直采)
公司:
产品分类:
公司分类: hydroxybenzene
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

ProductNameAHA1Protein
Description

YeastRecombinantAHA1Protein

ApplicationsWB,SDS-PAGE,FunctionalAssay
ConcentrationLot/batchspecific.Seeincludeddatasheet.
ConjugatesHistag

Properties

StorageBuffer12.5mMHepesbufferpH7.2,10mMNaCl,50%glycerol
StorageTemperature-20ºC
ShippingTemperatureBlueIceor4ºC
PurificationAffinityPurified
Specificity~405kDa
CiteThisProductYeastRecombinantAHA1Protein(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SPR-314)
CertificateofAnalysisThisproducthasbeencertified>90%pureusingSDS-PAGEanalysis.

BIOLOGicalDescription

AlternativeNamesAha1Protein,SHSA1Protein,HSPC322Protein,p38Protein
ResearchAreasCancer,HeatShock,CellSignaling,Chaperones,Trafficking
CellularLocalizationCytoplasm
AccessionNumberNM_001180522.1
GeneID851800
SwissProtQ12449
ScientificBackgroundAha1isamemberoftheHSP90cochaperonefamily,andisthoughttostimulateHSP90ATPaseactivitybycompetingwithp23andotherco-chaperonesforHSP90binding(1,2).ItmayaffectastepintheendoplasmicreticulumtoGolgitrafficking.Aha1alsointeractswithHSPCA/HSP90andwiththecytoplasmictailofthevesicularstomatistisvirusglycoproteins(VSVG)(3).Aha1isexpressedinnumeroustissues,includingthebrain,heart,skeletalmuscle,andkidney,andatlowlevels,theliverandplacenta.Aha1mightbeapotentialtherapeuticstrategytoincreasesensitivitytoHSPinhibitors(4).
References1.HainzlO.,LapinaM.C.,BuchnerJ.,RichterK.(2009)JBiolChem.Epub.
2.HarstA.,LinH.,ObermannW.M.(2005)BiochemJ.387(pt.3):789-796.
3.LotzG.P.,BrychzyA.,HeinzS.,ObermannW.M.(2008)JCellSci.121(pt.5):717-723.
4.HolmesJ.L.,SharpS.Y.,HobbsS.,WorkmanP.(2008)CancerRes.68(4):1188-1197.

ProductImages

<p>SDS-PAGE of ~38kDa his-tagged yeast Aha1 protein (SPR-314).</p>

SDS-PAGEof~38kDahis-taggedyeastAha1protein(SPR-314).

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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。