StressMarq/AG 1517/SIH-427-25MG/25-mg
商品编号:
SIH-427-25MG
市场价:
¥6900.00
美元价:
4140.00
产品分类:
酚
公司分类:
hydroxybenzene
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Overview:
ProductName | AG1517 |
Description | EGFRkinaseinhibitor |
Purity | >98%(TLC) |
CASNo. | 153436-54-5 |
MolecularFormula | C16H14BrN3O2 |
MolecularWeight | 360.2 |
Properties
StorageTemperature | -20ºC |
ShippingTemperature | ShippedAmbient |
ProductType | Inhibitor |
Solubility | SolubleinDMSO |
Source | Synthetic |
Appearance | Whitetooff-whitesolid |
SMILES | COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)Br)OC.Cl |
InChI | InChI=1S/C16H14BrN3O2/c1-21-14-7-12-13(8-15(14)22-2)18-9-19-16(12)20-11-5-3-4-10(17)6-11/h4-9H,1-2H3,(H,18,19,20) |
InChIKey | LSPANGZZENHZNJ-UHFFFAOYSA-N |
SafetyPhrases | Classification:Acutetoxicity,Oral(Category3)Skinirritation(Category2)Seriouseyedamage(Category1)Specifictargetorgantoxicity-singleexposure(Category3)SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection.Hazardstatements:H301Toxicifswallowed.H315Causesskinirritation.H318Causesseriouseyedamage.H335MaycauserespiratoryirritationPrecautionarystatements:P261Avoidbreathingdust/fume/gas/mist/vapours/spray.P280Wearprotectivegloves/eyeprotection/faceprotection.P301+P310IFSWALLOWED:ImmediatelycallaPOISONCENTERordoctor/physician.P305+P351+P338IFINEYES:Rinsecautiouslywithwaterforseveralminutes.Removecontactlenses,ifpresentandeasytodo.Continuerinsing. |
CiteThisProduct | AG1517(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-427) |
BIOLOGicalDescription
AlternativeNames | 4-[(3-Bromophenyl)amino]-6,7-dimethoxyquinazolinehydrochloride,AG1517,PD153035,SU5271,ZM252868,PD153,035,SU5271,4-(3-Bromoanilino)-6,7-dimethoxyquinazoline |
ResearchAreas | Cancer,Apoptosis,CancerGrowthInhibitors,CellSignaling,TyrosineKinaseInhibitors |
PubChemID | 4705 |
ScientificBackground | AG1517isapotentandselectiveATPcompetitiveinhibitoroftheepidermalgrowthfactorreceptortyrosinekinaseEGFR. |
References | 1.KunkelM.W.,etal.(1996)InvestigationalNewDrugs.13(4):295–302. |
ProductImages
ChemicalstructureofAG1517(SIH-427),aEGFRtyrosinekinaseinhibitor.CAS#:153436-54-5.MolecularFormula:C16H14BrN3O2.MolecularWeight:360.2g/mol.
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。