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当前位置: 首页 > 产品中心 > hydroxybenzene > StressMarq/AG 1517/SIH-427-5MG/5-mg
商品详细StressMarq/AG 1517/SIH-427-5MG/5-mg
StressMarq/AG 1517/SIH-427-5MG/5-mg
StressMarq/AG 1517/SIH-427-5MG/5-mg
商品编号: SIH-427-5MG
市场价: ¥1700.00
美元价: 1020.00
产地: 美国(厂家直采)
公司:
产品分类:
公司分类: hydroxybenzene
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

ProductNameAG1517
Description

EGFRkinaseinhibitor

Purity>98%(TLC)
CASNo.153436-54-5
MolecularFormulaC16H14BrN3O2
MolecularWeight360.2

Properties

StorageTemperature-20ºC
ShippingTemperatureShippedAmbient
ProductTypeInhibitor
SolubilitySolubleinDMSO
SourceSynthetic
AppearanceWhitetooff-whitesolid
SMILESCOC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)Br)OC.Cl
InChIInChI=1S/C16H14BrN3O2/c1-21-14-7-12-13(8-15(14)22-2)18-9-19-16(12)20-11-5-3-4-10(17)6-11/h4-9H,1-2H3,(H,18,19,20)
InChIKeyLSPANGZZENHZNJ-UHFFFAOYSA-N
SafetyPhrasesClassification:Acutetoxicity,Oral(Category3)Skinirritation(Category2)Seriouseyedamage(Category1)Specifictargetorgantoxicity-singleexposure(Category3)SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection.Hazardstatements:H301Toxicifswallowed.H315Causesskinirritation.H318Causesseriouseyedamage.H335MaycauserespiratoryirritationPrecautionarystatements:P261Avoidbreathingdust/fume/gas/mist/vapours/spray.P280Wearprotectivegloves/eyeprotection/faceprotection.P301+P310IFSWALLOWED:ImmediatelycallaPOISONCENTERordoctor/physician.P305+P351+P338IFINEYES:Rinsecautiouslywithwaterforseveralminutes.Removecontactlenses,ifpresentandeasytodo.Continuerinsing.
CiteThisProductAG1517(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-427)

BIOLOGicalDescription

AlternativeNames4-[(3-Bromophenyl)amino]-6,7-dimethoxyquinazolinehydrochloride,AG1517,PD153035,SU5271,ZM252868,PD153,035,SU5271,4-(3-Bromoanilino)-6,7-dimethoxyquinazoline
ResearchAreasCancer,Apoptosis,CancerGrowthInhibitors,CellSignaling,TyrosineKinaseInhibitors
PubChemID4705
ScientificBackgroundAG1517isapotentandselectiveATPcompetitiveinhibitoroftheepidermalgrowthfactorreceptortyrosinekinaseEGFR.
References1.KunkelM.W.,etal.(1996)InvestigationalNewDrugs.13(4):295–302.

ProductImages

<p>Chemical structure of AG 1517 (SIH-427), a EGFR tyrosine kinase inhibitor. CAS #: 153436-54-5. Molecular Formula: C16H14BrN3O2. Molecular Weight: 360.2 g/mol.</p>

ChemicalstructureofAG1517(SIH-427),aEGFRtyrosinekinaseinhibitor.CAS#:153436-54-5.MolecularFormula:C16H14BrN3O2.MolecularWeight:360.2g/mol.

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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。