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当前位置: 首页 > 产品中心 > Electrophoretic_buffer > StressMarq/Anti-Abl2 Antibody (pTyr439 + pThr440)/SPC-906D-A488/100-µl
商品详细StressMarq/Anti-Abl2 Antibody (pTyr439 + pThr440)/SPC-906D-A488/100-µl
StressMarq/Anti-Abl2 Antibody (pTyr439 + pThr440)/SPC-906D-A488/100-µl
StressMarq/Anti-Abl2 Antibody (pTyr439 + pThr440)/SPC-906D-A488/100-µl
商品编号: SPC-906D-A488
市场价: ¥6840.00
美元价: 4104.00
产地: 美国(厂家直采)
公司:
产品分类: 电泳缓冲液
公司分类: Electrophoretic_buffer
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

Product Name Abl2 Antibody (pTyr439 + pThr440)
Description

Rabbit Anti-Human Abl2 (pTyr439 + pThr440) Polyclonal

Species Reactivity Human
Applications WB, AM
Antibody Dilution WB (1:250); optimal dilutions for assays should be determined by the user.
Host Species Rabbit
Immunogen Species Human
Immunogen A phospho-specific peptide corresponding to residues surrounding Tyr439 and Thr440 of human Abl2 (AA3437-443)
Conjugates Alkaline Phosphatase, APC, ATTO 390, ATTO 488, ATTO 565, ATTO 594, ATTO 633, ATTO 655, ATTO 680, ATTO 700, Biotin, FITC, HRP, PE/ATTO 594, PerCP, RPE, Streptavidin, Unconjugated

Properties

Storage Buffer PBS pH7.4, 50% glycerol, 0.025% Thimerosal
Storage Temperature -20ºC
Shipping Temperature Blue Ice or 4ºC
Purification Peptide Affinity Purified
Clonality Polyclonal
Specificity Detects 128.343 kDa.
Cite This Product StressMarq Biosciences Cat# SPC-906, RRID: AB_2706707
Certificate of Analysis A 1:250 dilution of SPC-906 was sufficient for detection of Abl2 (pTyr439 + pThr440) in 10 µg of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.

Biological Description

Alternative Names Abelson tyrosine protein kinase 2 Antibody, ABL2 Antibody, ARG Antibody, Tyrosine kinase ARG Antibody
Research Areas Cancer, Cell Signaling, Oncoproteins, Protein Phosphorylation, Tumor Biomarkers, Tyrosine Kinases
Cellular Localization Cytoplasm, Cytoskeleton
Accession Number NP_009298
Gene ID 27
Swiss Prot P42684
Scientific Background ABL2 (Arg) is a widely expressed, 128 kDa, non-receptor protein-tyrosine kinases that is structurally related to Abl1. It features SH3 and SH2 domains, a protein- tyrosine kinase domain, and a nuclear localization domain. It shares many functions with Abl1, which includes cytoskeleton remodelling through phosphorylation of enzymes responsible for cytoskeleton rearrangements for signalling, adhesion, and movement as well as microtuble subunits, TUBA1 and TUBB. It also contains F-actin binding region to bundle and regulate actin cytoskeletal structure. It possesses autocatalytic activity and the ability to phosphorylate its inhibitor ABI1 to regulate itself.

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  ATTO 488
Overview:

  • High fluorescence yield
  • High photostability
  • Very hydrophilic
  • Excellent solubility in water
  • Very little aggregation
  • New dye with net charge of -1
  • Molar Mass: 804 g/mol 

ATTO 488 Datasheet

  ATTO 488 Fluorophore Excitation and Emission SpectraOptical Properties:

λex = 501 nm

λem = 523 nm

εmax = 9.0×104

Φf = 0.80

τfl = 4.1 ns

Brightness = 72

Laser = 488 nm

Filter set = FITC

 

品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。