STRESTMARQ/抗Abl1抗体（pTyr264）/SPC-904D-BI/100-µl-免疫在线蚂蚁淘旗下平台

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商品详细STRESTMARQ/抗Abl1抗体（pTyr264）/SPC-904D-BI/100-µl

STRESTMARQ/抗Abl1抗体（pTyr264）/SPC-904D-BI/100-µl

商品编号： SPC-904D-BI

品牌： StressMarq Biosciences

市场价： ¥6760.00

美元价： 4056.00

产地：美国(厂家直采)

公司：

产品分类：电泳缓冲液

公司分类： Electrophoretic_buffer

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Overview:

Product Name Abl1 Antibody (pTyr264)

Description

Rabbit Anti-Human Abl1 (pTyr264) Polyclonal

Species Reactivity Human

Applications WB, AM

Antibody Dilution WB (1:250); optimal dilutions for assays should be determined by the user.

Host Species Rabbit

Immunogen Species Human

Immunogen A phospho-specific peptide corresponding to residues surrounding Tyr264 of human Abl1- pY469 (AA466-472)

Conjugates

Alkaline Phosphatase, APC, ATTO 390, ATTO 488, ATTO 565, ATTO 594, ATTO 633, ATTO 655, ATTO 680, ATTO 700, Biotin, FITC, HRP, PE/ATTO 594, PerCP, RPE, Streptavidin, Unconjugated

Properties

Storage Buffer	PBS pH7.4, 50% glycerol, 0.025% Thimerosal
Storage Temperature	-20ºC
Shipping Temperature	Blue Ice or 4ºC
Purification	Peptide Affinity Purified
Clonality	Polyclonal
Specificity	Detects 122.945 kDa.
Cite This Product	StressMarq Biosciences Cat# SPC-904, RRID: AB_2706671
Certificate of Analysis	A 1:250 dilution of SPC-904 was sufficient for detection of Abl1 (pTyr264) in 10 µg of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.

Biological Description

Alternative Names	Abelson tyrosine protein kinase 1 Antibody, ABL Antibody, c ABL Antibody, p150 Antibody, bcr/abl Antibody
Research Areas	Cancer, Cell Signaling, Epigenetics and Nuclear Signaling, Oncoproteins, Protein Phosphorylation, Transcription, Tumor Biomarkers, Tyrosine Kinases
Cellular Localization	Cytoplasm, Cytoskeleton, Mitochondrion, Nucleus
Accession Number	NP_005148
Gene ID	25
Swiss Prot	P00519
Scientific Background	ABL1 is a widely-expressed, non-receptor protein-tyrosine kinase. It is stabilized in the inactive form by an association between the SH3 domain and the SH2-TK linker region, interactions of the N-terminal cap, and contributions from an N-terminal myristoyl group and phospholipids. It is activated by autophosphorylation as well as by Src-family kinase-mediated phosphorylation. It can also be activated by RIN1 binding to the SH2 and SH3 domains. As it is stimulated by cell death inducers and DNA-damage, it is likely that the wild-type form of Abl1 is actually a tumour -suppressor protein. The normal active form of Abl1 is nuclear, and it is sequestered into the cytoplasm by interaction with 14-3-3 through Thr-735. It localizes to the mitochondria under conditions of oxidative stress.

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Biotin

Properties:

Binds tetrameric avidin proteins including Streptavidin and neuravidin with very high affinity
Molar mass: 244.31 g/mol
Formula: C₁₀H₁₆N₂O₃S
Applications: Western blot, immunohistochemistry, and ELISA

Biotin Datasheet

品牌介绍

StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。

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