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当前位置: 首页 > 产品中心 > Electrophoretic_buffer > STRESTMARQ/抗ABCG2抗体/SPC-1317D-P594/100-µl
商品详细STRESTMARQ/抗ABCG2抗体/SPC-1317D-P594/100-µl
STRESTMARQ/抗ABCG2抗体/SPC-1317D-P594/100-µl
STRESTMARQ/抗ABCG2抗体/SPC-1317D-P594/100-µl
商品编号: SPC-1317D-P594
市场价: ¥6180.00
美元价: 3708.00
产地: 美国(厂家直采)
公司:
产品分类: 电泳缓冲液
公司分类: Electrophoretic_buffer
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

ProductNameABCG2Antibody
Description

RabbitAnti-HumanABCG2Polyclonal

SpeciesReactivityHuman
ApplicationsWB,IHC
AntibodyDilutionWB(1:2000),IHC(1:200);optimaldilutionsforassaysshouldbedeterminedbytheuser.
HostSpeciesRabbit
ImmunogenSpeciesHuman
ImmunogenAsynthesizedpeptidederivedfromhumanABCG2
ConjugatesAlkalinePhosphatase,APC,ATTO390,ATTO488,ATTO565,ATTO594,ATTO633,ATTO655,ATTO680,ATTO700,Biotin,FITC,HRP,PE/ATTO594,PerCP,RPE,Streptavidin,Unconjugated

Properties

StorageBufferPBSpH7.4,50%glycerol,150mMNaCl,0.02%sodiumazide
StorageTemperature-20ºC
ShippingTemperatureBlueIceor4ºC
PurificationAffinityPurified
ClonalityPolyclonal
IsotypeIgG
SpecificityDetectsendogenouslevelsoftotalABCG2
CiteThisProductStressMarqBiosciencesCat#SPC-1317,RRID:AB_2713493
CertificateofAnalysisA1:1000dilutionofSPC-1317wassufficientfordetectionofABCG2in10µgofmousekidneycelllyatesbyECLimmunoblotanalysisusingGoatAnti-RabbitIgG:HRPasthesecondaryantibody.

BIOLOGicalDescription

AlternativeNamesABCtransporterantibodyABC15antibodyABCG2antibodyABCG2antibodyABCG2_HUMANantibodyABCPantibodyATPbindingcassettesubfamilyG(WHITE)member2antibodyATPbindingcassettetransporterG2antibodyATP-bindingcassettesub-familyGmember2antibodyBCRPantibodyBCRP1antibodyBMDPantibodyBreastcancerresistanceproteinantibodyCD338antibodyCDw338antibodyCDw338antigenantibodyEST157481antibodyGOUT1antibodyMGC102821antibodyMitoxantroneresistanceassociatedproteinantibodyMitoxantroneresistance-associatedproteinantibodyMRXantibodyMultidrugresistanceeffluxtransportATPbindingcassettesubfamilyG(WHITE)member2antibodyMXRantibodyMXR1antibodyPlacentaspecificATPbindingcassettetransporterantibodyPlacentaspecificMDRproteinantibodyPlacenta-specificATP-bindingcassettetransporterantibodyUAQTL1antibody
CellularLocalizationCellmembrane,Mitochondrionmembrane
AccessionNumberNP_004818.2
GeneID9429
SwissProtQ9UNQ0
ScientificBackgroundABCG2(BCRP1/ABCP/MXR)isamemberoftheATP-bindingcassettetransporterfamilythatfunctionsasATP-dependenttransportersforawidevarietyofchemicalcompoundsandareassociatedwithdrug-resistanceincancercells.ABCG2isaheavilyglycosylatedtransmembraneproteinwithsixtransmembranespanningregionsconsistentwithitfunctioningasahalf-transporter.TheABCfamilycanexistaseitherfull-lengthtransportersorashalf-transportersthatformfunctionaltransportersthroughhomo-orheterodimerization.Originallythoughttoplayaroleindrugresistanceduetoitsresistancetoanumberofchemotherapeuticdrugs,ABCG2hasalsobeenfoundinthekidney,andstemcellpopulations.StudiesalsosuggestthatitcanbeusedasacellsurfaceMarkertoidentifyhematopoieticstemcellswithinthebonemarrowfractionoflineagenegativecells.TheexpressionofABCG2appearsgreatestonCD34-cellsandisdownregulatedwiththeacquisitionofCD34onthecellsurface.
References1.ZhouS.,etal.(2001)Nat.Medicine.7:1028.
2.DoyleL.A.andRossD.D.(2003)Oncogene.22:7340-58.
3.AllenJ.D.etal.(1999)CancerRes.59:4237-41.
4.DoyleL.A.,etal.(1998)ProcNatlAcadSciUSA.95:15665-70.
5.AllikmetsR.,etal.(1998)CancerRes.58:5337-9.
6.MiyakeK.,etal.(1999)CancerRes.59:8-13.
7.RobeyR.W.,etal.(2001)ClinCancerRes.7:145-52.ZhouS.,etal.(2001)Nat.Medicine.7:1028.

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 PE/ATTO594
PE/ATTO594isatandemconjugate,wherePEisexcitedat535nmandtransfersenergytoATTO594viaFRET(fluorescenceresonanceenergytransfer),whichemitsat627nm.
Overview:
  • Highfluorescenceyield
  • HighphotostABIlity
  • Veryhydrophilic
  • Excellentsolubilityinwater
  • Verylittleaggregation

PE/ATTO594Datasheet

PE-ATTO 594 Fluorophore Conjugate Excitation and Emission SpectraOpticalProperties:

λex =535nm

λem =627 nm

Laser = 488to561nm

 

品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。