STRESTMARQ/抗ABCG2抗体/SPC-1317D-BI/100-µl-免疫在线蚂蚁淘旗下平台

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商品详细STRESTMARQ/抗ABCG2抗体/SPC-1317D-BI/100-µl

STRESTMARQ/抗ABCG2抗体/SPC-1317D-BI/100-µl

商品编号： SPC-1317D-BI

品牌： StressMarq Biosciences

市场价： ¥5960.00

美元价： 3576.00

产地：美国(厂家直采)

公司：

产品分类：电泳缓冲液

公司分类： Electrophoretic_buffer

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Overview:

ProductName ABCG2Antibody

Description

RabbitAnti-HumanABCG2Polyclonal

SpeciesReactivity Human

Applications WB,IHC

AntibodyDilution WB(1:2000),IHC(1:200);optimaldilutionsforassaysshouldbedeterminedbytheuser.

HostSpecies Rabbit

ImmunogenSpecies Human

Immunogen AsynthesizedpeptidederivedfromhumanABCG2

Conjugates

AlkalinePhosphatase,APC,ATTO390,ATTO488,ATTO565,ATTO594,ATTO633,ATTO655,ATTO680,ATTO700,Biotin,FITC,HRP,PE/ATTO594,PerCP,RPE,Streptavidin,Unconjugated

Properties

StorageBuffer	PBSpH7.4,50%glycerol,150mMNaCl,0.02%sodiumazide
StorageTemperature	-20ºC
ShippingTemperature	BlueIceor4ºC
Purification	AffinityPurified
Clonality	Polyclonal
Isotype	IgG
Specificity	DetectsendogenouslevelsoftotalABCG2
CiteThisProduct	StressMarqBiosciencesCat#SPC-1317,RRID:AB_2713493
CertificateofAnalysis	A1:1000dilutionofSPC-1317wassufficientfordetectionofABCG2in10µgofmousekidneycelllyatesbyECLimmunoblotanalysisusingGoatAnti-RabbitIgG:HRPasthesecondaryantibody.

BIOLOGicalDescription

AlternativeNames	ABCtransporterantibodyABC15antibodyABCG2antibodyABCG2antibodyABCG2_HUMANantibodyABCPantibodyATPbindingcassettesubfamilyG(WHITE)member2antibodyATPbindingcassettetransporterG2antibodyATP-bindingcassettesub-familyGmember2antibodyBCRPantibodyBCRP1antibodyBMDPantibodyBreastcancerresistanceproteinantibodyCD338antibodyCDw338antibodyCDw338antigenantibodyEST157481antibodyGOUT1antibodyMGC102821antibodyMitoxantroneresistanceassociatedproteinantibodyMitoxantroneresistance-associatedproteinantibodyMRXantibodyMultidrugresistanceeffluxtransportATPbindingcassettesubfamilyG(WHITE)member2antibodyMXRantibodyMXR1antibodyPlacentaspecificATPbindingcassettetransporterantibodyPlacentaspecificMDRproteinantibodyPlacenta-specificATP-bindingcassettetransporterantibodyUAQTL1antibody
CellularLocalization	Cellmembrane,Mitochondrionmembrane
AccessionNumber	NP_004818.2
GeneID	9429
SwissProt	Q9UNQ0
ScientificBackground	ABCG2(BCRP1/ABCP/MXR)isamemberoftheATP-bindingcassettetransporterfamilythatfunctionsasATP-dependenttransportersforawidevarietyofchemicalcompoundsandareassociatedwithdrug-resistanceincancercells.ABCG2isaheavilyglycosylatedtransmembraneproteinwithsixtransmembranespanningregionsconsistentwithitfunctioningasahalf-transporter.TheABCfamilycanexistaseitherfull-lengthtransportersorashalf-transportersthatformfunctionaltransportersthroughhomo-orheterodimerization.Originallythoughttoplayaroleindrugresistanceduetoitsresistancetoanumberofchemotherapeuticdrugs,ABCG2hasalsobeenfoundinthekidney,andstemcellpopulations.StudiesalsosuggestthatitcanbeusedasacellsurfaceMarkertoidentifyhematopoieticstemcellswithinthebonemarrowfractionoflineagenegativecells.TheexpressionofABCG2appearsgreatestonCD34-cellsandisdownregulatedwiththeacquisitionofCD34onthecellsurface.
References	1.ZhouS.,etal.(2001)Nat.Medicine.7:1028. 2.DoyleL.A.andRossD.D.(2003)Oncogene.22:7340-58. 3.AllenJ.D.etal.(1999)CancerRes.59:4237-41. 4.DoyleL.A.,etal.(1998)ProcNatlAcadSciUSA.95:15665-70. 5.AllikmetsR.,etal.(1998)CancerRes.58:5337-9. 6.MiyakeK.,etal.(1999)CancerRes.59:8-13. 7.RobeyR.W.,etal.(2001)ClinCancerRes.7:145-52.ZhouS.,etal.(2001)Nat.Medicine.7:1028.

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Biotin

Properties:

BindstetramericavidinproteinsincludingStreptavidinandneuravidinwithveryhighaffinity
Molarmass:244.31g/mol
Formula:C₁₀H₁₆N₂O₃S
Applications:Westernblot,immunohistochemistry,andELISA

BiotinDatasheet

品牌介绍

StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。

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