StressMarq/A83 01/SIH-423-5MG/5-mg
商品编号：
SIH-423-5MG
市场价：
¥1640.00
美元价：
984.00
产品分类：
电泳缓冲液
公司分类：
Electrophoretic_buffer
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | A8301 |
| Description | ALKkinaseinhibitor |
| Purity | >98%(HPLC) |
| CASNo. | 909910-43-6 |
| MolecularFormula | C25H19N5S |
| MolecularWeight | 421.5 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | Solubleto50mMinDMSO |
| Source | Synthetic |
| Appearance | Whitetobeigepowder |
| SMILES | CC1=NC(=CC=C1)C2=NN(C=C2C3=CC=NC4=CC=CC=C34)C(=S)NC5=CC=CC=C5 |
| InChI | InChI=1S/C25H19N5S/c1-17-8-7-13-23(27-17)24-21(19-14-15-26-22-12-6-5-11-20(19)22)16-30(29-24)25(31)28-18-9-3-2-4-10-18/h2-16H,1H3,(H,28,31) |
| InChIKey | HIJMSZGHKQPPJS-UHFFFAOYSA-N |
| SafetyPhrases | Classification:Acutetoxicity,Oral(Category4)Skinirritation(Category2)Eyeirritation(Category2A)Specifictargetorgantoxicity-singleexposure(Category3),RespiratorysystemSafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection.Hazardstatements:H302Harmfulifswallowed.H315Causesskinirritation.H319Causesseriouseyeirritation.H335Maycauserespiratoryirritation..Precautionarystatements:P261Avoidbreathingdust/fume/gas/mist/vapours/spray.P305+P351+P338IFINEYES:Rinsecautiouslywithwaterforseveralminutes.Removecontactlenses,ifpresentandeasytodo.Continuerinsing. |
| CiteThisProduct | A8301(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-423) |
BIOLOGicalDescription
| AlternativeNames | 3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide,A-83-01,A83-01 |
| ResearchAreas | Cancer,Apoptosis,CancerGrowthInhibitors,CellSignaling,TyrosineKinaseInhibitors |
| PubChemID | 16218924 |
| ScientificBackground | A83-01isaselectiveinhibitorofTGF-βtypeIreceptorALK5kinase.ItblocksphosphorylationofSmad2andinhibitsTGF-β-inducedepithelial-to-mesenchymaltransition.A83-01alsoinhibitsthetranscriptionalactivityinducedbyTGFβtypeIreceptorALK-5,activintypeIBreceptorALK-4andnodaltypeIreceptorALK-7. |
| References | 1.LiW.,etal.(2009)StemCell4(1):16–19. 2.CherukuriP.,etal.(2012).PloSOne.7(11):e50066. |
ProductImages
ChemicalstructureofA8301(SIH-423),aALKkinaseinhibitor.CAS#:909910-43-6.MolecularFormula:C25H19N5S.MolecularWeight:421.5g/mol.
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
