StressMarq/6BIO/SIH-422-5MG/5-mg
商品编号：
SIH-422-5MG
市场价：
¥1500.00
美元价：
900.00
产品分类：
电泳缓冲液
公司分类：
Electrophoretic_buffer
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | 6BIO |
| Description | PDK1kinaseinhibitor |
| Purity | >98%(HPLC) |
| CASNo. | 667463-62-9 |
| MolecularFormula | C16H10BrN3O2 |
| MolecularWeight | 356.2 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | Solubleto10mMinDMSOandto10mMinethanol |
| Source | Synthetic |
| Appearance | Darkredsolid |
| SMILES | C1=CC=C2C(=C1)/C(=NO)/C(=C/3C4=C(C=C(C=C4)Br)NC3=O)/N2 |
| InChI | InChI=1S/C16H10BrN3O2/c17-8-5-6-9-12(7-8)19-16(21)13(9)15-14(20-22)10-3-1-2-4-11(10)18-15/h1-7,20,22H,(H,19,21)/b15-13+ |
| InChIKey | WNWSUJQVZJJGLF-FYWRMAATSA-N |
| SafetyPhrases | Classification:Skinirritation(Category2),H315Eyeirritation(Category2A),H319Specifictargetorgantoxicity-singleexposure(Category3),Respiratorysystem,H335SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection.Hazardstatements:H315Causesskinirritation.H319Causesseriouseyeirritation.H335Maycauserespiratoryirritation.Precautionarystatements:P261Avoidbreathingdust/fume/gas/mist/vapours/spray.P264Washskinthoroughlyafterhandling.P271Useonlyoutdoorsorinawell-ventilatedarea.P280Wearprotectivegloves/eyeprotection/faceprotection.P302+P352IFONSKIN:Washwithplentyofsoapandwater.P304+P340IFINHALED:Removevictimtofreshairandkeepatrestinapositioncomfortableforbreathing.P305+P351+P338IFINEYES:Rinsecautiouslywithwaterforseveralminutes.Removecontactlenses,ifpresentandeasytodo.Continuerinsing.P312CallaPOISONCENTERordoctor/physicianifyoufeelunwell.P321Specifictreatment(seesupplementalfirstaidinstructionsonthislabel).P332+P313Ifskinirritationoccurs:Getmedicaladvice/attention.P337+P313Ifeyeirritationpersists:Getmedicaladvice/attention.P362Takeoffcontaminatedclothingandwashbeforereuse.P403+P233Storeinawell-ventilatedplace.Keepcontainertightlyclosed.P405Storelockedup.P501Disposeofcontents/containertoanapprovedwastedisposalplant. |
| CiteThisProduct | 6BIO(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-422) |
BIOLOGicalDescription
| AlternativeNames | (2’Z,3’E)-6-Bromoindirubin-3′-oxime,6-BIO,6BIO,(3Z)-6-Bromo-3-[(3E)-3-(hydroxyimino)-1,3-dihydro-2H-indol-2-ylidene]-1,3-dihydro-2H-indol-2-one |
| ResearchAreas | CellSignaling |
| PubChemID | 11405589 |
| ScientificBackground | 6BIOisaninhibitorofphosphoinositide-dependentkinase1(PDK1),andapotent,reversIBLeandATP-competitiveinhibitorofglycogensynthasekinase-3α/β(GSK-3α/β).Itmaintainsself-renewalandpluripotencyinembryonicstemcellsviaactivationoftheWntsignalingpathway. |
| References | 1.ValerioA.,etal.(2011)J.NeuRochem.116(6):1148–1159. 2.YasuharaR.,etal.(2010)J.Biol.Chem.285(1):317–327. 3.MeijerL.,etal.(2003)Chem.&Bio.10(12):1255–1266. |
ProductImages
Chemicalstructureof6BIO(SIH-422),aESCself-renewal.CAS#:667463-62-9.MolecularFormula:C16H10BrN3O2.MolecularWeight:356.2g/mol.
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
