StressMarq/5-Azacytidine/SIH-345-50MG/50-mg
商品编号：
SIH-345-50MG
市场价：
¥720.00
美元价：
432.00
产品分类：
电泳缓冲液
公司分类：
Electrophoretic_buffer
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | 5-Azacytidine |
| Description | DNAhypomethylationagent |
| Purity | >98%(TLC);NMR(Conforms) |
| CASNo. | 320-67-2 |
| MolecularFormula | C8H12N4O5 |
| MolecularWeight | 244.2 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | Solublein25mg/mlDMSOor12mg/mlWater |
| Source | Synthetic |
| Appearance | WhiteSolid |
| SMILES | C1=NC(=NC(=O)N1[[email protected]]2[[email protected]@H]([[email protected]@H]([[email protected]](O2)CO)O)O)N |
| InChI | InChI=1S/C8H12N4O5/c9-7-10-2-12(8(16)11-7)6-5(15)4(14)3(1-13)17-6/h2-6,13-15H,1H2,(H2,9,11,16)/t3-,4-,5-,6-/m1/s1 |
| InChIKey | NMUSYJAQQFHJEW-KVTDHHQDSA-N |
| SafetyPhrases | Classification:Harmful-Maybeharmfulifinhaled,swallowed,orabsorbedthroughskin.SafetyPhrases:S22-DonotbreathedustS36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotectionS24/25-AvoidcontactwithskinandeyesHazardStatements:H302-HarmfulifswallowedH350–MaycausecancerPrecautionaryStatements:P201–Obtainspecialinstructionsbeforeuse.P308+P313–Ifexposedorconcerned:Getmedicaladvice/attention |
| CiteThisProduct | 5-Azacytidine(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-345) |
BIOLOGicalDescription
| AlternativeNames | 4-Amino-1-β-D-ribofuranosyl-1,3,5-triazin-2(1H)-one;Ladakamycin;U-18496;NSC-102816;5-AzaC |
| ResearchAreas | Cancer,CellSignaling,Epigenetics |
| PubChemID | 9444 |
| ScientificBackground | DNAmethyltransferaseinhibitor.IncorporatesintoDNAformingcovalentadductswithcellularDNMT1,depletingenzymeactivity.Inducesdemethylationandreactivationofsilencedgenes.Improvestheefficiencyofreprogrammingofstemcells;inducesdifferentiationofmesenchymalstemcellsintocardiomyocytes. |
| References | 1.Schneider-StockR.,etal.(2005)JPharmacolExpTher.312(2):525-536. 2.MikkelsenT.S.,etal.,(2008)Nature.454(7200):49-55. 3.QianQ.,etal.,(2012)StemCellsDev.21(1):67-75. |
ProductImages
Chemicalstructureof5-Azacytidine(SIH-345),aDNAhypomethylationagent.CAS#:320-67-2.MolecularFormula:C8H12N4O5.MolecularWeight:244.2g/mol.
ProductCitations(0)
Currentlytherearenocitationsforthisproduct.
品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
