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当前位置: 首页 > 产品中心 > Electrophoretic_buffer > 应激MARQ/24(S)-羟基胆固醇/SIH-384-1MG/1-mg
商品详细应激MARQ/24(S)-羟基胆固醇/SIH-384-1MG/1-mg
应激MARQ/24(S)-羟基胆固醇/SIH-384-1MG/1-mg
应激MARQ/24(S)-羟基胆固醇/SIH-384-1MG/1-mg
商品编号: SIH-384-1MG
市场价: ¥1900.00
美元价: 1140.00
产地: 美国(厂家直采)
公司:
产品分类: 电泳缓冲液
公司分类: Electrophoretic_buffer
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

ProductName24(S)-Hydroxycholesterol
Description

LXRligand

Purity>98%
CASNo.474-73-7
MolecularFormulaC27H46O2
MolecularWeight402.7

Properties

StorageTemperature-20ºC
ShippingTemperatureShippedAmbient
ProductTypeLigand
SolubilitySolubleinethanol(10mg/ml)orDMSO(10mg/ml-requireswarmingupto~40°C).
SourceSynthetic
AppearanceWhitesolid
SMILES[[email protected]]24([[email protected]]([[email protected]@H]1CC=C3[[email protected]@]([[email protected]]1CC2)(CC[[email protected]](O)C3)C)CC[[email protected]@H]4[[email protected]@H](CC[[email protected]@H](C(C)C)O)C)C
InChIInChI=1S/C27H46O2/c1-17(2)25(29)11-6-18(3)22-9-10-23-21-8-7-19-16-20(28)12-14-26(19,4)24(21)13-15-27(22,23)5/h7,17-18,20-25,28-29H,6,8-16H2,1-5H3/t18-,20+,21+,22-,23+,24+,25+,26+,27-/m1/s1
InChIKeyIOWMKBFJCNLRTC-XWXSNNQWSA-N
SafetyPhrasesClassification:Caution.Substancenotyetfullytested.SafetyPhrases:S22-DonotbreathedustS36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotectionS24/25-Avoidcontactwithskinandeyes
CiteThisProduct24(S)-Hydroxycholesterol(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-384)

BIOLOGicalDescription

AlternativeNames(3β,24S)-Cholest-5-ene-3,24-diol
ResearchAreasCellSignaling
PubChemID121948
ScientificBackgroundEndogenousagoNISTforthenuclearreceptorLXR.Importantmetaboliteofcholesterolinthebrain.Displaysneurotoxiceffectsonhumanneuroblastomacells.Cerebrospinalfluidconcentrationsof24(S)-hydroxycholesterolareincreasedinpatientswithAlzheimer’sdiseaseandmildcognitiveimpairment.
References1.ChawlaA.,etal.(2001)Science.294(5548):1866-70.
2.LütjohannD.,etal.(1996)Proc.Natl.Acad.Sci.USA.93(18):9799-804.
3.KölschH.,etal.(1999)BrainRes.818(1):171-5.
4.SchönknechtP.,etal.(2002)Neurosci.Lett.324(1):83-5.
5.LeoniV.,etal.(2006)Neurosci.Lett.397(1-2):83-7.

ProductImages

<p>Chemical structure of 24(S)-Hydroxycholesterol (SIH-384), a LXR ligand. CAS #: 474-73-7. Molecular Formula: C27H46O2 . Molecular Weight: 402.7 g/mol.</p>

Chemicalstructureof24(S)-Hydroxycholesterol(SIH-384),aLXRligand.CAS#:474-73-7.MolecularFormula:C27H46O2.MolecularWeight:402.7g/mol.

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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。