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当前位置: 首页 > 产品中心 > Electrophoretic_buffer > STRESS MARQ/115-7C/SIH-123-25MG/25MG
商品详细STRESS MARQ/115-7C/SIH-123-25MG/25MG
STRESS MARQ/115-7C/SIH-123-25MG/25MG
STRESS MARQ/115-7C/SIH-123-25MG/25MG
商品编号: SIH-123-25MG
市场价: ¥9000.00
美元价: 5400.00
产地: 美国(厂家直采)
公司:
产品分类: 电泳缓冲液
公司分类: Electrophoretic_buffer
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

ProductName115-7C
Description

Hsp70Activator

Purity>98%
MolecularFormulaC23H22Cl2N2O5
MolecularWeight477.34

Properties

StorageTemperature-20ºC
ShippingTemperatureShippedAmbient
ProductTypeActivator
SolubilitySolubleinDMSO(20mg/ml)
SourceSynthetic
AppearanceWhiteSolid
SMILESCC1=C(C(NC(=O)N1CCCC(=O)O)c2ccc(cc2Cl)Cl)C(=O)OCc3ccccc3
InChIInChI=1S/C23H22Cl2N2O5/c1-14-20(22(30)32-13-15-6-3-2-4-7-15)21(17-10-9-16(24)12-18(17)25)26-23(31)27(14)11-5-8-19(28)29/h2-4,6-7,9-10,12,21H,5,8,11,13H2,1H3,(H,26,31)(H,28,29)
InChIKeyUHBVLBSCOSTTAV-UHFFFAOYSA-N
SafetyPhrasesClassification:Caution:Substancenotyetfullytested.SafetyPhrases:S22-DonotbreathedustS24/25-AvoidcontactwithskinandeyesS36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection
CiteThisProduct115-7C(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-123)

BIOLOGicalDescription

AlternativeNames4-(5-((benzyloxy)carbonyl)-4-(2,4-dichlorophenyl)-6-methyl-2-oxo-3,4-dihydropyrimidin-1(2H)-yl)butanoicacid,SWO2
ResearchAreasCancer,HeatShock
ScientificBackground115-7cactivatesHsp70ATPaseturnoverrateandpromotesHsp70substraterefolding.ItbindstotheIIAsuBDomainofDnaKandpromotestheDnaK-DnaJcomplex.EquivalentwithSW02.
References1.Wisenetal.,(2010)ACSChem.Biol.,5:611-622.
2.Jinwaletal.(2009)J.Neurosci.29:12079.
3.Chafekaretal.(2012)ACSChemBiol.7:1556.
4.Walteretal.(2011)J.Biol.Chem.286:40486

ProductImages

<p>Chemical structure of 115-7C (SIH-123), a Hsp70 Activator. Molecular Formula: C₂₃H₂₂Cl₂N₂O₅. Molecular Weight: 477.34 g/mol.</p>

Chemicalstructureof115-7C(SIH-123),aHsp70Activator.MolecularFormula:C₂₃H₂₂Cl₂N₂O₅.MolecularWeight:477.34g/mol.

ProductCitations(1)

OtherCitations

Hsp70MayBeaMolecularRegulatorofSchistosomeHostInvasion.

Ishida,K.andJollyE.R.(2016)PLoSNeglTropDis.10(9):e0004986.

PubMedID:27611863Applications:Invitroactivation

品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。