StressMarq/115-7C/SIH-123-5MG/5-mg
商品编号：
SIH-123-5MG
市场价：
¥2400.00
美元价：
1440.00
产品分类：
电泳缓冲液
公司分类：
Electrophoretic_buffer
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | 115-7C |
| Description | Hsp70Activator |
| Purity | >98% |
| MolecularFormula | C23H22Cl2N2O5 |
| MolecularWeight | 477.34 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Activator |
| Solubility | SolubleinDMSO(20mg/ml) |
| Source | Synthetic |
| Appearance | WhiteSolid |
| SMILES | CC1=C(C(NC(=O)N1CCCC(=O)O)c2ccc(cc2Cl)Cl)C(=O)OCc3ccccc3 |
| InChI | InChI=1S/C23H22Cl2N2O5/c1-14-20(22(30)32-13-15-6-3-2-4-7-15)21(17-10-9-16(24)12-18(17)25)26-23(31)27(14)11-5-8-19(28)29/h2-4,6-7,9-10,12,21H,5,8,11,13H2,1H3,(H,26,31)(H,28,29) |
| InChIKey | UHBVLBSCOSTTAV-UHFFFAOYSA-N |
| SafetyPhrases | Classification:Caution:Substancenotyetfullytested.SafetyPhrases:S22-DonotbreathedustS24/25-AvoidcontactwithskinandeyesS36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection |
| CiteThisProduct | 115-7C(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-123) |
BIOLOGicalDescription
| AlternativeNames | 4-(5-((benzyloxy)carbonyl)-4-(2,4-dichlorophenyl)-6-methyl-2-oxo-3,4-dihydropyrimidin-1(2H)-yl)butanoicacid,SWO2 |
| ResearchAreas | Cancer,HeatShock |
| ScientificBackground | 115-7cactivatesHsp70ATPaseturnoverrateandpromotesHsp70substraterefolding.ItbindstotheIIAsuBDomainofDnaKandpromotestheDnaK-DnaJcomplex.EquivalentwithSW02. |
| References | 1.Wisenetal.,(2010)ACSChem.Biol.,5:611-622. 2.Jinwaletal.(2009)J.Neurosci.29:12079. 3.Chafekaretal.(2012)ACSChemBiol.7:1556. 4.Walteretal.(2011)J.Biol.Chem.286:40486 |
ProductImages
Chemicalstructureof115-7C(SIH-123),aHsp70Activator.MolecularFormula:C₂₃H₂₂Cl₂N₂O₅.MolecularWeight:477.34g/mol.
ProductCitations(1)
OtherCitations
Hsp70MayBeaMolecularRegulatorofSchistosomeHostInvasion.
Ishida,K.andJollyE.R.(2016)PLoSNeglTropDis.10(9):e0004986.
PubMedID:27611863Applications:Invitroactivation
品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
